Serveur d'exploration Chloroquine

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Innate antiviral defenses in body fluids and tissues

Identifieur interne : 002523 ( Main/Exploration ); précédent : 002522; suivant : 002524

Innate antiviral defenses in body fluids and tissues

Auteurs : Samuel Baron [États-Unis] ; Indra Singh [États-Unis] ; Ashok Chopra [États-Unis] ; Dorian Coppenhaver [États-Unis] ; Jingzhi Pan [États-Unis]

Source :

RBID : ISTEX:82148751380E5AE7BD6A40B2002DB57875C5F43F

English descriptors

Abstract

Abstract: Innate, non-specific, resistance mechanisms are important barriers to pathogens, particularly delaying virus multiplication at the onset of infections. These innate defense mechanisms include a series of mechanical barriers, pre-existing inhibitory molecules, and cellular responses with antimicrobial activity. The antiviral activities of these innate inhibitors reside in a variety of partly characterized substances. This review presents the innate antiviral inhibitors in cell cultures, urine, serum, the gastrointestinal tract, the nervous system, tissues of crustaceans, and saliva. Medical adaptation of the innate antiviral defense mechanisms may be useful for prevention and treatment of viral infections.

Url:
DOI: 10.1016/S0166-3542(00)00126-1


Affiliations:


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Le document en format XML

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<term>Acta virol</term>
<term>Agents chemother</term>
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<term>Ammonium salts</term>
<term>Anti6iral</term>
<term>Anti6iral research</term>
<term>Antiviral</term>
<term>Antiviral activities</term>
<term>Antiviral activity</term>
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<term>Baron</term>
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<term>Carbohydrate</term>
<term>Cell cultures</term>
<term>Chopra</term>
<term>Colostrum</term>
<term>Coppenhaver</term>
<term>Crab</term>
<term>Crab inhibitor preparation</term>
<term>Crustacean</term>
<term>Early defenses</term>
<term>European study group</term>
<term>Experimental animals</term>
<term>Gamma inhibitor</term>
<term>Gastrointestinal</term>
<term>Gastrointestinal tract</term>
<term>Heterosexual transmission</term>
<term>Host defenses</term>
<term>Human serum</term>
<term>Human virus</term>
<term>Human virus type</term>
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<term>Lipid</term>
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<term>Moiety</term>
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<term>Molecular weight</term>
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<term>Nervous system</term>
<term>Neuramide</term>
<term>Oral cavity</term>
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<term>Poast</term>
<term>Porcine</term>
<term>Porcine mucosal</term>
<term>Proc</term>
<term>Rathova</term>
<term>Replication</term>
<term>Replication cycle</term>
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<term>Salivary</term>
<term>Salivary inhibitors</term>
<term>Secretory leukocyte protease inhibitor</term>
<term>Seminal</term>
<term>Semliki forest virus</term>
<term>Serum inhibitors</term>
<term>Sexual transmission</term>
<term>Sindbis</term>
<term>Sindbis virus</term>
<term>Singh</term>
<term>Stomatitis</term>
<term>Subsequent infection</term>
<term>Target cells</term>
<term>Titer</term>
<term>Uids</term>
<term>Urine</term>
<term>Utib</term>
<term>Vaccinia viruses</term>
<term>Vero cells</term>
<term>Vesicular</term>
<term>Vesicular stomatitis virus</term>
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<div type="abstract" xml:lang="en">Abstract: Innate, non-specific, resistance mechanisms are important barriers to pathogens, particularly delaying virus multiplication at the onset of infections. These innate defense mechanisms include a series of mechanical barriers, pre-existing inhibitory molecules, and cellular responses with antimicrobial activity. The antiviral activities of these innate inhibitors reside in a variety of partly characterized substances. This review presents the innate antiviral inhibitors in cell cultures, urine, serum, the gastrointestinal tract, the nervous system, tissues of crustaceans, and saliva. Medical adaptation of the innate antiviral defense mechanisms may be useful for prevention and treatment of viral infections.</div>
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